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 Ústav  patologickej 
 fyziológie
(informácie)

Informácia o pracovisku

História pracoviska

Zoznam pracovníkov

Učitelia na ústave

Projekty pracoviska (granty) 

Diplomové práce pracoviska

Výber z publikovaných prác

Knihy, učebnice, skriptá 

Oddelenie klinickej patofyziológie

Pokusné zariadenie pracoviska


Študijný program  všeobecné lekárstvo 

Organizácia výučby a skúšok

Harmonogram výučby a rozvrh

Výberové prednášky a semináre

Sylaby (otázky) (patologická fyziológia)

Voliteľné predmety (3.-6.ročník) 

OZNAMY - výučba, skúšky

TESTY

Odporúčaná literatúra


Študijný program zubné lekárstvo 

Organizácia výučby a skúšok
Harmonogram výučby a rozvrh
Sylaby(otázky) (patologická fyziológia)

OZNAMY - výučba, skúšky

TESTY

Odporúčaná literatúra


Študijný program biomedicínska fyzika

Harmonogram výučby a rozvrh

Sylaby látky      

Odporúčaná literatúra


Study programme General medicine
(English  speaking students)

Study rules and integral organization

Program of seminars and practical lessons + time schedule

Sylabus (questions) (Pathologic physiology)        

NEWS - credits and exams

Optional subjects

Study Literature  

TESTS


Study programme Dentistry 
(English  speaking students)

Study rules and integral organization

Program of seminars and practical lessons + time schedule

Sylabus (questions) (Pathologic physiology)    

NEWS - credits and exams

Optional subjects

Study Literature 

TESTS

 


 

  

                                                                               

Vybrané publikácie pracovníkov ústavu  2005-2016

     

                                                                              

          2005

  • Bernadic M, Hubka P, Slavkovsky P, Petrasova H, Holzerova J, Maasova D, Zlatos L, Mladosievicova B, Hulin I:  High resolution electrocardiography in healthy dogs. Time domain parameters and comparison of the non-stationary (Wigner distribution) versus standard stationary frequency domain nalysis methods. Physiological Research 54, No 5, 2005.

  • Celec P, Gardlik R, Palffy R, Hodosy J, Stuchlik S, Drahovska H, Stuchlikova M, Minarik G, Lukacs J, Jurkovicova I, Hulin I, Turna J, Jakubovsky J, Kopani M, Danisovic L, Jandzik D, Kudela M, Yonemitsu Y: The use of transformed Escherichia coli for experimental angiogenesis induced by regulated in situ production of vascular endothelial growth factor--an alternative gene therapy. Medical Hypotheses, 64(3): 505-11, 2005

  • Celec P: Hemojuvelin: a supposed role in iron metabolism one year after its discovery. Journal of Molecular Medicine, 83(7): 521-5, 2005

  • Ferenčík M, Štvrtinová V, Hulín I: Defects in regulation of local immune responses resulting. Clin. Developt. Imunol. 2005, 12(3), 225-234

  • Hubka P., Bernadic M., Hulin I.: Long-term monitoring of the changes in SA ECG after coronary artery occlusion  and i.c. endothelin-1 injection in dogs. Physiol. Res., 2005, Apr. 26.

  • Mladosievičová B, Paulovič P, Foltinová A, Hulín I: Frequency-domain abnormalities 
    of the QRS complex after anthracycline therapy. Pediatric Blood Cancer, 2005, 45(4):P.L.038:553-554

  • Mravec B, Bodnar I, Uhereczky G, Nagy GM, Kvetnansky R, Palkovits M: Formalin attenuates the stress-induced increase in plasma epinephrine levels. J Neuroendocrinol 2005; 17: 727-732

  • Mravec B: A new focus on interoceptive properties of adrenal medulla. Auton Neurosci 2005; 120: 10-17

  • Šimko F, Luptak I, Matuskova J, Krajcirovicova K, Sumbalova Z, Kucharska J, Gvozdjakova, Simko J, Babal P, Pechanova O, Bernatova I: L-arginine fails to protect against myoacardial remodeling in L-NAME-induced hypertension. Eur J Clin Invest 35/6/, 2005, 362-358.  

  • Šimko F, Pelouch V, Torok J, Luptak I, Matuskova J, Pechanova O, Babal P: Protein remodeling of the heart ventricles in hereditary hypertriglyceridemic heart. J Biomed Sci 12, 2005, 103-111. 

          2006

  • Bernadič M., Traubner P., Kukurová E., Bernadičová H.: Asserting Bologna declaration in restructuring of school system at Comenius University Medical School Bratislava. Bratisl. Lek. Listy, 2006, 107, č. 4, s. 123-125.

  • Celec P, Hodosy J: Student scientific activity at the Bratislava medical faculty 2000–2004. A scientometric study. Central European Journal of Medicine, 1(2): 172-178, 2006

  • Celec P, Ostatnikova D, Hodosy J, Skoknova M, Putz Z, Kudela M: Infradian rhythmic variations of salivary estradiol and progesterone in healthy men. Biological Rhythm Research, 37(1): 37-44, 2006

  • Filipcik P, Cente M, Ferencik M, Hulin I, Novak M: The role of oxidative stress in the pathogenesis of Alzheimer's disease. Bratisl Lek Listy. 2006;107(9-10):384-94.

  • Holesova Z, Ostatnikova D, Minarik G, Ficek A, Putz Z, Celec P: Has the brain 
    a gender? Homeostasis, 44(1-2): 40-48, 2006

  • Hubka P, Bernadic M, Hulin I: Long-term monitoring of the changes in signal-averaged ECG after coronary artery occlusion and intracoronary endothelin-1 injection in dogs. Physiol Res. 2006;55(1):9-14.

  • Kopani M, Celec P, Danisovic L, Michalka P, Biro C: Oxidative stress and electron spin resonance. Clinica Chimica Acta, 364(1-2): 61-6, 2006  

  • Kvetnansky R, Bodnar I, Shahar T, Uhereczky G, Krizanova O, Mravec B:  Effect 
    of lesion of A5 and A7 brainstem noradrenergic areas or transection of brainstem pathways on sympathoadrenal activity in rats during immobilization stress. Neurochem Res 2006; 31: 267-275.

  • Mravec B, Gidron Y, Kukanova B, Bizik J, Kiss A, Hulin I: Neural – endocrine – immune complex in the central modulation of tumorigenesis: facts, assumptions, and hypotheses. J Neuroimmunol 2006; 180: 104-116.

  • Palffy R, Gardlik R, Hodosy J, Behuliak M, Resko P, Radvansky J, Celec P: Bacteria in gene therapy: bactofection versus alternative gene therapy. Gene Therapy, 13(2): 101-5, 2006

  • Pechanova O, Matuskova J, Capikova D, Jendekova L, Paulis L, Simko F: Effect of spironolactone and captopril on nitric oxide and S-nitrosothiol formation in kidney of L-NAME-treated rats. Kidney Int. 2006 Jul, 70(1):170-6. Epub 2006 May 17.

  • Pechanova O, Matuskova J, Capikova D, Jendekova L, Paulis L, Simko F. Effect 
    of spironolactone and captopril on nitric oxide and S-nitrosothiol formation in kidney 
    of L-NAME-treated rats. Kidney International 70:170-176, 2006.

  • Urbanová D, Urban L, Carter A, Maasova D, Mladosievicova B. Cardiac troponins--biochemical markers of cardiac toxicity after cytostatic therapy. Neoplasma. 2006;53(3):183-90.

  • Urbanova D, Urban L, Carter A, Maasova D, Mladosievicova B: Cardiac troponins - Biochemical markers of cardiac toxicity after cytostatic therapy.  Neoplasma 53, 3, 2006,  183-190 

  • Zicha J, Pechanova O, Cacanyiova S, Cebova M, Kristek F, Torok J, Simko F, Dobesova Z, Kunes J: Hereditary hypertriglyceridemic rat: a suitable model of cardiovascular disease and metabolic syndrome?  Physiol Res. 2006, 55 Suppl 1:S49-63

  • Zilka N, Ferencik M, Hulin I: Neuroinflammation in Alzheimer's disease: protector 
    or promoter? Bratisl Lek Listy. 2006;107(9-10):374-83.

 

          2007

  • Herichová I, Mravec B, Stebelová K, Križanová O, Jurkovičová D, Kvetňanský R, Zeman M: Rhythmic clock gene expression in heart, kidney and some brain nuclei involved in blood pressure control in hypertensive TGR(mREN-2)27 rats. Mol Cell Biochem 2007; 296: 25-34.

  • Mladosievicova B, Carter A, Kristova V:  Genetic tests for predicting the toxicity and efficacy of anticancer chemotherapy. Neoplasma. 2007;54(3):181-8.

  • Mladosievičová B, Kaiserová E, Foltinová A, Petrášová H: Dlhodobé́ nežiaduce účinky terapie u pacientov vyliečených z detskej malignity. Klin. Onkol. 20 (1), 2007, 18-22

  • Mravec B: Does the vagus nerve mediate the effects of polyunsaturated fatty acid treatment on behavioral, neuroendocrine and cytokine changes elicited by exogenous interleukin-1β challenge? J Neuroimmunol 2007; 185: 208–210.

  • Paulis L, Líšková S, Pintérová M, Dobešová Z, Kuneš J, Zicha J. Nifedipine-sensitive noradrenergic vasoconstriction is enhanced in spontaneously hypertensive rats: the influence of chronic captopril treatment. Acta Physiol 191: 255-266, 2007.

  • Paulis L, Simko F. Blood pressure modulation and cardiovascular protection by melatonin: Potential mechanisms behind. Physiol Res 56:(6): 671-684, 2007.

  • Paulis L, Simko F. LA419, a novel nitric oxide donor, prevents cardiac remodeling via the endothelial nitric oxide synthase pathway: NO donors as a means of antiremodeling? Hypertension 50(6): 1009-1011, 2007.

  • Paulis L, Važan R, Šimko F, Pecháňová O, Styk J, Babál P, Janega P. Morphological Alterations and NO-Synthase Expression in the Heart after Continuous Light Exposure of Rats. Physiol Res 56(Suppl 2): S71-S76, 2007.

  • Pechanova O, Zicha J, Paulis L, Zenebe W, Dobesova Z, Kojsova S, Jendekova L, Sladkova M, Dovinova I, Simko F, Kunes J:  The effect of N-acetylcysteine and melatonin in adult spontaneously hypertensive rats with established hypertension. 
    Eur J Pharmacol. 2007 Apr 30, 561(1-3):129-36. Epub 2007 Feb 1.

  • Pechanova O, Zicha J, Paulis L, Zenebe W, Dobesova Z, Kojsova S, Jendekova L, Sladkova M, Dovinova I, Simko F, Kunes J. The effect of N-acetylcysteine and melatonin in adult spontaneously hypertensive rats with established hypertension. 
    Eur J Pharmacol 561(1-3): 129-36, 2007.

  • Simko F, Paulis L. Melatonin as a potential antihypertensive treatment. J Pineal Res 42(4): 319-322, 2007.

  • Simko F, Paulis L:  Melatonin as a potential antihypertensive treatment. J Pineal Res. 2007 Apr, 42(4):319-22.

  • Székács D, Bodnár I, Mravec B, Kvetnansky R, Vizi ES, Nagy GM, Fekete MIK: 
    The peripheral noradrenergic terminal as possible site of action of salsolinol as prolactoliberin. Neurochem Int 2007; 50: 427-434.

  • Šimko F, Matúšková J, Ľupták I, Pinčíková T, Krajčírovičová K, Štvrtina S, Pomšár J, Pelouch V, Paulis L, Pecháňová O. Spironolactone Differently Influences Remodeling of the Left Ventricle and Aorta in L-NAME-Induced Hypertension. Physiol Res 56(Suppl 2): S25-S32, 2007.

  • Važan R, Janega P, Hojná S, Zicha J, Šimko F, Pecháňová O, Styk J, Paulis L. The Effect of Continuous Light Exposure of Rats on Cardiac Response to Ischemia-Reperfusion and NO-Synthase Activity. Physiol Res 56(Suppl 2): S63-S69, 2007.

 

          2008

  • Bucová M., Lietava J., Mrazek F., Petrek M., Petrkova J., Bernadic M., 
    Buckingham T.: Association of chronic stable angina pectoris with MCP-1-2518 A/G single nucleotide polymorphism in the Slovak population. Letter to the editor. Clinica Chimica Acta, 392, 2008, s. 71-72.

  • Mravec B, Gidron Y, Hulin I: Neurobiology of cancer: interactions between nervous, endocrine and immune systems as a base for monitoring and modulating the tumorigenesis by the brain. Semin Cancer Biol 2008; 18: 150-63.

  • Paulis L, Matuskova J, Adamcova M, Pelouch V, Simko J, Krajcirovicova K, 
    Potacova A, Hulin I, Janega P, Pechanova O, Simko F. Regression of left ventricular hypertrophy and aortic remodelling in NO-deficient hypertensive rats: effect of l-arginine and spironolactone. Acta Physiol (Oxf) 194(1):45-55, 2008.

  • Paulis L, Zicha J, Kunes J, Hojna S, Behuliak M, Celec P, Kojsova S, Pechanova O, Simko F. Regression of L-NAME-induced hypertension: The role of NO and endothelium-derived constricting factor. Hypertens Res 31(4):793-804, 2008.

  • Pirnik Z, Bundzikova J, Bizik J, Hulin I, Kiss A, Mravec B: Activity of brainstem groups of catecholaminergic cells in tumor bearing rats: response to immobilization stress. Ann NY Acad Sci 2008; 1148: 141-7.

  • Simko F, Paulis L. Chronotherapy beyond blood pressure reduction? J Pineal Res 45:227-228, 2008.

  • Urbanova D, Urban L, Danova K, Simkova I. Natriuretic peptides: biochemical markers of anthracycline cardiac toxicity? Oncol Res. 2008;17(2):51-8.

 

          2009

  • Benova M, Stebelova K, Paulis L, Simko F, Zeman M. Effect of L-NAME-induced hypertension on melatonin receptors and melatonin levels in the pineal gland and the peripheral organs of rats. Hypertens Res 32(4):242-7, 2009.

  • Bucova M., Lietava J.,  Penz P., Mrazek F., Petrkova J., Bernadic M.,  Petrek M.: Association of MCP-1 -2518 A/G single nucleotide polymorphism with the serum level of CRP  in Slovak patients with ischemic heart disease, angina pectoris and hypertension. Mediators of Inflammation, Vol. 2009, ID 390 951, pp. 1-6.

  • Bucová M., Lietava J., Mrazek F., Petrkova J., Penz P., Bernadic M., Buckingham T.A.:  The MCP-1 – 2518(A/G) single nucleotide polymorphism is associated with ischemic heart disease and myocardial infarction in men in the Slovak population. Bratisl. Lek. Listy, 110, 2009, č. 7, s. 385-389.

  • Hudecová, K., Šimková, I., Gardlík, R., Bernadič, M.: Genetic screening of patients with hypertrophic cardiomyopathy – a new diagnostic strategy for risk stratification? Bratislava Medical Journal 110, 2009, č. 2, s. 83-90.

  • Mravec B, Ondicova K, Valaskova Z, Gidron Y, Hulin I: Neurobiological principles in the etiopathogenesis of disease: when diseases have a head. Med Sci Monit 2009; 15: RA6-16.

  • Paulis L, Pechanova O, Zicha J, Barta A, Gardlik R, Celec P, Kunes J, Simko F. Melatonin interactions with blood pressure and vascular function during L-NAME-induced hypertension. J Pineal Res in press, 2009.

  • Paulis L, Pechanova O, Zicha J, Krajcirovicova K, Barta A, Pelouch V, Adamcova M, Simko F. Melatonin prevents fibrosis but not hypertrophy development in the left ventricle of NG-nitro-L-arginine-methyl ester hypertensive rats. J Hypertens 27(Suppl 6):S11-S16, 2009.

  • Pirnik Z, Bundzikova J, Francisty T, Cibulova E, Lackovicova L, Mravec B, Kiss A. Effect of Liver Ischemia-Reperfusion Injury on the Activity of Neurons in the Rat Brain. Cell Mol Neurobiol 2009; 29: 951-60.

  • Simko F, Pechanova O, Pelouch V, Krajcirovicova K, Mullerova M, Bednarova K, Adamcova M, Paulis L. Effect of melatonin, captopril, spironolactone and simvastatin on blood pressure and left ventricular remodelling in spontaneously hypertensive rats. 
    J Hypertens 27(Suppl 6):S5-S10, 2009.

  • Urbanová D, Bubanská E, Hrebík M, Mladosievicová B. Heart Transplantation in 
    a Childhood Leukemia Survivor. Experimental and Clinical Transplantation. 2009; Manuscript ID ECT-OA-10-09-0086; in press.

  • Urbanová D, Bubanská E, Hrebík M, Mladosievicová B. Severe heart failure in consequence of late anthracycline-induced cardiotoxicity. Klin Onkol. 2009;22(1):34-37.

  • Vranková S, Jendekova L, Paulis L, Sladkova M, Simko F, Pechanova O. Comparison of the effects of indapamide and captopril on the development of spontaneous hypertension. J Hypertens 27(Suppl 6):S42-S46, 2009.

  • Zeman M, Szántóová K, Stebelová K, Mravec B, Herichová I: Effect of rhythmic melatonin administration on clock gene expression in the suprachiasmatic nucleus and the heart of hypertensive TGR(mRen2)27 rats. J Hypertens 2009; 
    27 Suppl 6:S21-6.  

 

          2010

  • Mravec B. The role of the vagus nerve in stroke. Auton Neurosci 2010; 158: 8-12.

  • Ondicova K, Mravec B. Multilevel interactions between the sympathetic and parasympathetic nervous systems: a minireview. Endocr Regul 2010; 44: 69-75.

  • Ondicova K, Mravec B. Role of nervous system in cancer aetiopathogenesis. 
    Lancet Oncol 2010; 11: 596–601.

  • Ondicova K, Pecenak J, Mravec B. The role of the vagus nerve in depression. 
    Neuro Endocrinol Lett 2010; 31: 101-7.

  • Paulis L, Pechanova O, Zicha J, Barta A, Gardlik R, Celec P, Kunes J, Simko F. Melatonin interactions with blood pressure and vascular function during L-NAME-induced hypertension. J Pineal Res 2010; 48(2):102-108.  

  • Paulis L, Pechanova O, Zicha J, Liskova S, Celec P, Mullerova M, Kollar J, Behuliak M, Kunes J, Adamcova M, Simko F. Melatonin improves the restoration of endothelium-derived constricting factor signalling and inner diameter in the rat femoral artery after cessation of L-NAME treatment. J Hypertens 2010; 28(Suppl 1):S19-S24.

  • Paulis L, Unger T. Novel therapeutic targets for hypertension. Nat Rev Cardiol 2010;  7(8): 431-441.  

  • Pechanova O, Simko F. The role of nuclear factor kappa B and nitric oxide interaction in heart remodelling. J Hypertens. 2010 Sep; 28 Suppl 1: S39-44.

  • Putora PM, Paulis L, Plasswilm L. Automated Erythema Quantification in radiation therapy- a Java based tool. Applied Medical Informatics 2010; 26(1):1-6.  

  • Roziaková L, Mladosievicová B. Cardiovascular effects after hematopoietic stem cell transplantation. Vnitr Lek. 2010 Mar; 56(3):2 33-9.

  • Roziakova L, Mladosievicova B. Endocrine late effects after hematopoietic stem cell transplantation. Oncol Res. 2010; 18(11-12): 607-15.

  • Simko F, Pechanova O. Remodelling of the heart and vessels in experimental hypertension: advances in protection. J Hypertens. 2010 Sep; 28 Suppl 1: S1-6.

  • Simko F, Pechanova O, Pelouch V, Krajcirovicova K, Celec P, Palffy R, Bednarova K, Vrankova S, Adamcova M, Paulis L. Continuous light and L-NAME-induced left ventricular remodelling: different protection with melatonin and captopril. J Hypertens 2010; 28(Suppl 1): S13-S18.

  • Steckelings UM, Widdop RE, Paulis L, Unger T. The angiotensin AT2 receptor in left ventricular hypertrophy. J Hypertens 2010; 28(Suppl 1):S50-S55.  

  • Vrankova S, Parohova J, Barta A, Janega P, Simko F, Pechanova O .Effect of nuclear factor kappa B inhibition on L-NAME-induced hypertension and cardiovascular remodelling. O. J Hypertens. 2010 Sep; 28 Suppl 1: S45-9.

 

          2011

 

          2012

 

          2013

  • Altanerova V, Cihova M, Babic M, Rychly B, Ondicova K, Mravec B, Altaner C. 
    Human adipose tissue–derived mesenchymal stem cells expressing yeast
    cytosinedeaminase: uracil phosphoribosyltransferase inhibit intracerebral rat
    glioblastoma. Int J Cancer 2012; 130: 2455-63.

  • Babickova J, Tothova L, Boor P, Celec P: In vivo phage display - A discovery tool in molecular biomedicine. Biotechnology Advances, 31(8): 1247-1259, 2013.

  • Bernadič M.: Úvodník. Úvaha nad šálkou čaju. Vaskulárna medicína, 5, 2013, č. 2, 
    s. 55-56.

  • Celecova V, Kamodyova N, Tothova L, Kudela M, Celec P: Salivary markers of oxidative stress are related to age and oral health in adult non-smokers. Journal of Oral Pathology & Medicine, 42 (3): 263-266, 2013.

  • Danyel LA, Schmerler P, Paulis L, Unger T, Steckelings UM. Impact of AT2-receptor stimulation on vascular biology, kidney function, and blood pressure. Integr Blood Press Control 6:153-161, 2013.

  • Gardlik R, Bartonova A, Celec P: Therapeutic DNA vaccination and RNA interference in inflammatory bowel disease. International Journal of Molecular Medicine, 32 (2): 492-496, 2013.

  • Hrenák J, Arendášová K, Rajkovičová R, Aziriová S, Repová K, Krajčírovičová K, Celec P, Kamodyová N, Bárta A, Adamcová M, Paulis L, Simko F. Protective effect of captopril, olmesartan, melatonin and compound 21 on doxorubicin-induced nephrotoxicity in rats. Physiol Res. 62(Suppl 1):S181-S189, 2013.

  • Chocholova A, Soltysova A, Minarik G, Cierna I, Sufliarska S, Mladosievicova B.: Tiopurine s-methyltransferase gene polymorphisms in a healthy slovak population and pediatric patients with inflammatory bowel disease. Nucleosides Nucleotides Nucleic Acids. 2013;32(5):239-46.

  • Nádvorník P., Čierny G., Bernadič M.: The future of spinal cord stereotaxy. Bratisl. Lek. Listy, 114, 2013, č. 5, s. 297-299.

  • Namsolleck P, Boato F, Schwengel K, Paulis L, Matho KS, Geurts N, Thöne-Reineke C, Lucht K, Seidel K, Hallberg A, Dahlöf B, Unger T, Hendrix S, Steckelings UM. AT2-receptor stimulation enhances axonal plasticity after spinal cord injury by upregulating BDNF expression. Neurobiol Dis 51:177-191, 2013.

  • Repová-Bednárová K, Aziriová S, Hrenák J, Krajčírovičová K, Adamcová M, Paulis L, Simko F. Effect of captopril and melatonin on fibrotic rebuilding of the aorta in 24 hour light-induced hypertension. Physiol Res. 62(Suppl 1):S135-S141, 2013.

  • Rovenský J., Lukáč J., Tuchyňová A., Bernadič M.: Systemic lupus erythematosus in Slovakia – survey results. Reumatologia (Rheumatology), 51, 2013, č. 3, s. 185-188.

  • Roziaková L, Mladosievičová B.: Role of cardiac bio-markers in monitoring of cardiotoxicity after hematopoietic stem cell transplantation. Vnitr Lek. 2013 Nov; 59(11):996-1002. 

  • Schmerler P, Jeuthe S, O H-Ici D, Wassilew K, Lauer D, Kaschina E, Kintscher U, Müller S, Muench F, Kuehne T, Berger F, Unger T, Steckelings UM, Paulis L, Messroghli D. Mortality and Morbidity in Different Immunization Protocols for Experimental Autoimmune Myocarditis in Rats. Acta Physiol (Oxf) doi: 10.1111/apha.12227, 2014 [Epub ahead of print]  

  • Simko F, Paulis L. Antifibrotic effect of melatonin--perspective protection in hypertensive heart disease. Int J Cardiol. 168(3):2876-2877, 2013.

  • Simko F, Reiter RJ, Pechanova O, Paulis L. Experimental models of melatonin-deficient hypertension. Front Biosci (Landmark Ed). 8:616-625, 2013.

  • Slavic S, Lauer D, Sommerfeld M, Kemnitz UR, Grzesiak A, Trappiel M, Thöne-Reineke C, Baulmann J, Paulis L, Kappert K, Kintscher U, Unger T, Kaschina E. Cannabinoid receptor 1 inhibition improves cardiac function and remodelling after myocardial infarction and in experimental metabolic syndrome. J Mol Med (Berl) 91(7):811-823, 2013.

 

          2014  

 

          2015

 

  • Adamcová M, Lencová-Popelová O,  Jirkovský E,  Mazurová Y,  Palička V, Šimko F,  Geršl V,  Štěrba M: Experimental determination of diagnostic window of cardiac troponins in the development of chronic anthracycline cardiotoxicity and estimation of its predictive value.  International Journal of Cardiology. - Vol. 201 (2015), s. 358-367

  • Horváthová Ľ, Tillinger A,  Siváková I, Miková L, Mravec B, Bucová M: Chemical sympathectomy increases neutrophil-to-lymphocyteratio in tumor-bearing rats but does not influence cancer progression. Journal of Neuroimmunology. - Vol. 278, January (2015), s. 255-261.

  • Hrenák J, Paulis Ľ, Repová K, Aziriová S, Nagtegaal E, Reiter, Russel J, Šimko F: Melatonin and renal protection: novel perspectives from animal experiments and human studies (Review). Current Pharmaceutical Design. - Vol. 21, No. 7 (2015), s. 936-949.

  • Hrenák J, Paulis Ľ, Šimko F: N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP): Potential target molecule in research of heart, kidney and brain. Current Pharmaceutical Design. - Vol. 21, No. 35 (2015), s. 5135-5143

  • Lejavová K, Ondičová K, Horváthová Ľ, Hegedüsová N, Cubinková V, Vargovič P, Manz G, Filipčík P,  Mravec B, Novák M, Kvetňanský R: Stress-induced activation of the sympathoadrenal system is determined by genetic background in rat models of tauopathy.  Journal of Alzheimer's Disease. - Vol. 43, No. 4 (2015), s. 1157-1161

  • Miková L, Horváthová Ľ, Ondičová K, Tillinger A, Vannucci L, Bízik J, Gidron Y, Mravec B: Ambiguous effect of signals transmitted by the vagus nerve on fibrosarcoma incidence and survival of tumor-bearing rats. Neuroscience Letters. Vol. 593, April (2015), s. 90-94

  • Mravec B, Ondičová K, Tillinger A, Pečeňák J: Subdiaphragmatic vagotomy enhances stress-induced epinephrine release in rats.  Autonomic Neuroscience : Basic & Clinical. - Vol. 190 (2015), s. 20-25

  • Paulis Ľ, Rajkovičová R, Šimko F: New developments in the pharmacological treatment of hypertension: dead-end or a glimmer at the horizon?  Current Hypertension Reports [elektronický zdroj]. - Vol. 17, No. 6 (2015), Art. No. 42 [13 s.]

  • Roziaková Ľ, Mistrík M, Bátorová A, Kružliak P, Bojtárová E, Dúbrava J, Gergel J, Mladosievičová B: Can we predict clinical cardiotoxicity with cardiac biomarkers in patients after haematopoietic stem cell transplantation?  Cardiovascular Toxicology. - Vol. 15, No. 3 (2015), s. 210-216

  • Šimko F, Pecháňová O, Krajčirovičová K, Matúšková J, Pelouch V, Adamcová M, Paulis Ľ: Effects of captopril,spironolactone, and simvastatin on the cardiovascular system of non-diseased Wistar rats. International Journal of Cardiology. - Vol. 190, No. 1 (2015), s. 128-130

  • Mladosievičová B, Jurkovič R, Izakovičová Hollá L: Dentálne abnormality po protinádorovej liečbe v detskom veku = Dental abnormalities after treatment for childhood cancer. Klinická onkologie. - Roč. 28, č. 1 (2015), s. 20-23

  • Bernadič M, Kubišová K, Bernadič M: Patofyziologické východiská pre liečbu systémového lupus erythematosus = Pathophysiological backgrounds of systemic lupus erythematosus therapy. In: Rheumatologia. - Roč. 29, č. 2 (2015), s. 31-36

  • Géczová L, Šoltýsová A, Gécz J, Šufliarska S, Horáková J, Mladosievičová B: Avascular necrosis of bone in childhood cancer patients: a possible role of genetic susceptibility.  Bratislavské lekárske listy. - Roč. 116, č. 5 (2015), s. 289-295

  • Paulis L, Fauconnier J, Cazorla O, Thireau J, Soleti R, Vidal B, Ouillé A, Bartholome M, Bideaux P, Roubille F, Le Guennec JY, Andriantsitohaina R, Martínez MC, Lacampagne A. Activation of Sonic hedgehog signaling in ventricular cardiomyocytes exerts cardioprotection against ischemia reperfusion injuries. Sci Rep 23;5:7983, 2015.

 

 

   2016

 

  • Aziriová S, Repová K, Krajčirovičová K, Baka T, Zórad Š, Mojto V, Slavkovský P, Hodosy J, Adamcová M, Paulis Ľ, Šimko F: Effect of ivabradine, captopril and melatonin on the behaviour of rats in L-nitro-arginine methyl ester-induced hypertension. In: Journal of Physiology and Pharmacology. - Vol. 67, No. 6 (2016), s. 895-902

  • Hrenák J, Paulis Ľ, Šimko F: Angiotensin A/alamandine/MrgD axis: Another clue to understanding cardiovascular pathophysiology. In: International Journal of Molecular Sciences. - Vol. 17, No. 7 (2016), s. Art. No. 1098

  • Hrenák J, Paulis Ľ, Šimko F: Angiotensin A/alamandine/MrgD axis: Another clue to understanding cardiovascular pathophysiology. In: International Journal of Molecular Sciences. - Vol. 17, No. 7 (2016), s. Art. No. 1098

  • Mravec B, Lejavová K, Vargovič P, Ondičová K, Horváthová Ľ, Novák P, Manz G, Filipčík P, Novák M, Kvetňanský R: Tauopathy in transgenic (SHR72) rats impairs function of central noradrenergic system and promotes neuroinflammation. In: Journal of Neuroinflammation [elektronický zdroj]. - Vol. 13 (2016), Art. No. 15 [17 s.]

  • Paulis Ľ, Foulquier S, Namsolleck P, Recarti Ch, Steckelings Muscha U, Unger Th: Combined angiotensin receptor modulation in the management of cardio-metabolic disorders. In: Drugs. - Vol. 76, No. 1 (2016), s. 1-12

  • Šimko F, Baka T, Paulis Ľ, Reiter Russel J.: Elevated heart rate and nondipping heart rate as potential targets for melatonin: a review In: Journal of Pineal Research. - Vol. 61, No. 2 (2016), s. 127-137

  • Piteková B, Ravi S, Mladosievičová B, Shah S, Medveďová E, Ferenčík M, Heitner S, Scott E.C.: Cardiovascular considerations in multiple myeloma. In: Heart and Cardiology: Open Access [elektronický zdroj]. - Vol. 2, No. 2 (2016), Art. No. HCOA-2-011 [online]

  • Setteyová L, Bachárová L, Mladosievičová B: QT prolongation due to targeted anticancer therapy. In: OncoReview. - Vol. 6, No. 3 (2016), s. A103-A112

  • Pecháňová O, Paulis Ľ, Šimko F: Impact of melatonin on central blood pressure regulation. In: Activitas nervosa superior rediviva. - Vol. 58, No. 4 (2016), s. 99-104

  • Poljak Valášková Z, Hulín I, Maruščáková L, Carter A, Mladosievičová B: Androgen deprivation therapy and cardiovascular complications. In: Bratislavské lekárske listy. - Roč. 117, č. 10 (2016), s. 557-561 

   2017

 

  • Paulis L, Franke H, Simko F: Gene therapy for hypertension. Expert Opin Biol Ther. 2017 Nov;17(11):1345-1361. doi: 10.1080/14712598.2017.1364726. Epub 2017 Aug 17

  • Simko F, Pechanova O, Repova K, Aziriova S, Krajcirovicova K, Celec P, Tothova L, Vrankova S, Balazova L, Zorad S, Adamcova M:  Lactacystin-Induced Model of Hypertension in Rats: Effects of Melatonin and Captopril. Int J Mol Sci. 2017 Jul 25;18(8). pii: E1612. doi: 10.3390/ijms18081612

  • Sabaka P, Dukat A, Gajdosik J, Bendzala M, Caprnda M, Simko F:The effects of body weight loss and gain on arterial hypertension control: an observational prospective study. Eur J Med Res. 2017 Oct 25;22(1):43. doi: 10.1186/s40001-017-0286-5

  • van Thiel BS, Góes Martini A, Te Riet L, Severs D, Uijl E, Garrelds IM, Leijten FPJ, van der Pluijm I, Essers J, Qadri F, Alenina N, Bader M, Paulis L, Rajkovicova R, Domenig O, Poglitsch M, Danser AHJ: Brain Renin-Angiotensin System: Does It Exist?Hypertension. 2017 Jun;69(6):1136-1144. doi:10.1161/Hypertensionaha.116.08922. Epub 2017 Apr 10. PMID: 28396529

  • Demitrovicova L, Mikuskova E, Oravcova I, Cingelova S, Drgona L, Mladosievicova B: Infectious complications in chronic lymphocytic leukemia- a retrospective analysis: single institution experience. Neoplasma 2017;64(3):474-481.

  • Mladosievičová B: Kardiotoxicita u hematoonkologických pacientov. Kardiologická revue - Interní medicína. 2017;19(1):34-38.

  • Setteyová L, Mladosievičová B: Predĺženie QTc intervalu vyvolané systémovou liečbou nádorov / Prolongation of the QTc interval induced by systemic tumor therapy. Cardiology Lett 2017; 26 (5): 288-294.

  • Valaskova Z, Mladosievicova B, Maruscakova L, Hulin I: MicroRNA – Information about myocardial damage or biomarker of heart failure ? Cardiology Lett 2017;26(5):299-302.

  • Murín J, Mladosievičová B, Špánik S:  Position paper of the European Society of Cardiology on antitumour therapy and its cardiovascular toxicity. Cardiology Lett 2017;26(2):65-68.  

   2018

 

  • Poljak Z, Hulin I, Maruscakova L, Mladosievicova B:  Are GnRH and FSH potentially damaging factors in the cardiovascular system? PHARMAZIE, Apr 2, 73(4): 187-190

  • Foulquier S, Paulis L, Kaschina E, Namsolleck P, Unger T: Hormonal Systems. pp 81-106. In: Berbari AE and Mancia G. Disorders of blood pressure regulation. Springer International Publishing AG, Cham, Switzerland 2018, ISBN 978-3-319-59917-5

  • Krajcirovicova K, Aziriova S, Baka T, Repova K, Adamcova M, Paulis L, Simko F: Ivabradine does not impair anxiety-like behavior and memory in both healthy and L-NAME-induced hypertensive rats. Physiol Res. 2018;67(Supplementum 4):S655-S664.

  • Simko F, Baka T, Poglitsch M, Repova K, Aziriova S, Krajcirovicova K, Zorad S, Adamcova M, Paulis L:. Effect of Ivabradine on a Hypertensive Heart and the Renin-Angiotensin-Aldosterone System in L-NAME-Induced Hypertension. Int J Mol Sci. 2018;19(10).

  • Baka T, Simko F: Nondipping heart rate: A neglected cardiovascular risk factor based on autonomic imbalance? Auton Neurosc Basic Clin 2018;210:83-4

  • Baka T, Hodosy J, Krajcirovicova K, Repova K, Aziriova S, Domonkos E, Borbelyova V,  Slavkovsky P, Zorad S, Celec P, Paulis L, Simko F: 17β-Estradiol treatment reversed left ventricular dysfunction in castrated male rats: an echocardiographic study. Can J Physiol Pharmacol. 2018;96(8):850-854.

  • Simko F, Baka T, Krajcirovicova K, Repova K, Aziriova S, Zorad S, Poglitsch M, Adamcova M, Reiter RJ, Paulis L: Effect of melatonin on the renin-angiotensin-aldosterone system in L-NAME-induced hypertension. Molecules 2018;23(2).

  • Repova K, Krajcirovicova K, Mullerova M, Aziriova S, Baka T, Zorad S, Slavkovsky P, Hodosy J, Celec P, Adamcova M, Paulis L, Simko F:  Effect of melatonin on the behaviour of rats with continuous light-induced hypertension. Gen Physiol Biophys 2018;37(4):469-73.

  • Simko F, Adamcova M: What prevents cardioprotective drugs from reaching the market? Expert Rev Clin Pharmacol 2018;11(5):463-5.

 


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